Woman gives birth to healthy child with uterus from dead donor

Woman gives birth to healthy child with uterus from dead donor

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For the first time healthy child born from the womb of a dead donor

In Brazil, a woman with the womb of a dead organ donor gave birth to a healthy child. The uterus was removed after birth. Mother and daughter are doing fine. Such an intervention has never been successful.

Fulfill your desire to have children

Women who have no or too small a womb due to a genetic change from birth cannot give birth to children. But a transplant could fulfill many of these women wanting to have children. In 2013, a woman with a donor uterus had given birth to a healthy baby in Gothenburg (Sweden) for the first time worldwide. The then 36-year-old mother had had the organ transplanted only the year before. A child was born for the first time in Brazil with the womb of a dead donor.

Woman gave birth to child with the womb of a dead woman

For the first time in history, a woman gave birth to a child with the womb of a dead organ donor.

The baby was born in Brazil at the end of 2017, reports the team led by Dr. Dani Ejzenberg from the São Paulo University Hospital in the specialist magazine "The Lancet".

In September 2016, the then 32-year-old woman had a dead woman's uterus implanted in the Hospital das Clínicas, University of São Paulo and had become pregnant a few months later.

In the spring of 2016, the woman had undergone hormone treatment to remove eggs from her ovaries, which were frozen after artificial insemination.

The recipient suffers from the so-called Mayer-Rokitansky-Küster-Hauser syndrome (MRKHS), a congenital malformation in which the uterus is absent or only incompletely developed.

The woman who underwent the first uterine transplant in Germany also suffers from this syndrome.

The 45-year-old donor in Brazil had died after a brain hemorrhage, according to a BBC report. According to the information, she had given birth to three children in her life in a natural way.

The uterus was removed after birth

The successful transplant had taken about ten hours.

During the procedure, the donor organ was connected to the blood vessels and vagina. The recipient had to take drugs that suppress the immune system so that her body does not reject the organ.

She developed a regular cycle about five months after the operation.

Two months later, the doctors placed fertilized eggs in the patient's womb. She was pregnant only ten days later.

The child was born by caesarean section in the 36th week of pregnancy. The healthy girl weighed 2,550 grams and was 45 centimeters tall.

Now mother and daughter are doing well. Since the implanted uterus was removed immediately after the caesarean section, the woman no longer has to take immunosuppressive drugs.

Previous transplants from dead donors were unsuccessful

According to the “BBC”, ten donors had previously been transplanted, but all of them failed or miscarried.

The transplant in Brazil is therefore considered a decisive breakthrough and proof that such an intervention is even possible.

The doctors now hope to be able to help significantly more women with unfulfilled desire for children in the future.

A uterine transplant would not only be an option for women who do not have a functioning uterus due to a malformation, but also for those who have lost the organ due to an illness or accident.

Dr. Dani Ejzenberg said: "The first uterine transplants from live donors were a medical milestone that gave many infertile women the opportunity to have a child using appropriate donors and the required medical facilities."

But: "The need for a living donor is a major limitation because donors are rare and are typically family members or close friends."

Dr. Srdjan Saso of Imperial College London said the results were "extremely exciting".

"It enables the use of a much larger potential donor population, causes lower costs and avoids the surgical risks of living donors." (Ad)

Author and source information

Video: First. birth by woman with uterus transplant (August 2022).