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Artificial intelligence calculates the spread of cancerous tumors

Artificial intelligence calculates the spread of cancerous tumors


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AI could make cancer treatment more effective

Cancer is a deadly disease that affects more and more people around the world. Researchers have now used artificial intelligence to predict how the disease will progress and spread. This could help doctors develop the most effective treatment for each patient in the future.

In their current study, scientists from the Institute of Cancer Research London (ICR) and the University of Edinburgh found that artificial intelligence can be used to predict how cancer will develop and spread. The doctors published the results of their study in the English-language journal "Nature Methods".

AI can predict future genetic changes

The newly developed technology is considered by the experts revolver (Repeated Evolution of Cancer). They identify patterns in the DNA mutation within cancer. The information can then be used to predict future genetic changes.

The constantly changing structure of tumors is one of the greatest challenges in the treatment of cancer, the experts explain. However, if doctors could predict how a tumor would develop, they could intervene earlier and stop the cancer from progressing before it can develop or become resistant. This would significantly increase the patient's chance of survival.

Patterns of mutation in tumors can be predicted

The research team also found a link between certain sequences of repeated tumor mutations and the probability of survival. This suggests that repeating patterns of mutations in DNA could be used as an indicator of the prognosis to shape the future treatment of the disease. The doctors developed a new machine learning method that transfers the knowledge about tumors to similar patients. This method identifies patterns in the order in which genetic mutations occur in tumors, using the pattern of the mutation of one tumor to predict the pattern of another tumor.

Samples from 178 patients were examined

The researchers used 768 samples from tumors from 178 patients, which had already been taken in previous studies for lung, breast, kidney and colon cancer. They analyzed the data within each type of cancer to accurately identify and compare changes in the tumors. By identifying repetitive patterns and combining them with current knowledge of cancer biology and cancer development, scientists could predict the future development of tumors. If tumors with specific patterns develop resistance to treatment, this new method could be used to predict whether certain patients will be affected in the future.

AI can make predictions about the development of tumors

A powerful tool for artificial intelligence could be developed, which can make predictions about the future development steps of tumors based on certain patterns, says study author Dr. Andrea Sottoriva from the Institute of Cancer Research London. This also applies to mutations that have so far remained hidden in complex data sets.

Cancer often develops unpredictably

Hopefully, this new tool can be used to overcome one of the major dangers of cancer - the fact that it usually develops unpredictably, the scientists explain. The tool could be used in the future to intervene at an earlier point in time and predict the next step of the cancer.

Predicting the development of tumors enables more effective treatment

If it can be predicted how a tumor will develop, treatment could be changed before adaptation and drug resistance occur, so that medical professionals would always be one step ahead of cancer. This new approach, which uses AI, could make it possible to personalize the treatment in more detail and earlier than before, and to adapt it to the properties of each individual tumor. The experts also emphasize that predictions could be made about how a tumor will develop in the future. (as)

Author and source information


Video: Anant Madabhushi, PhD - Artificial intelligence and cancer treatment (July 2022).


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